Chloramphenicol is a broad-spectrum antibiotic that typically stops bacterial growth by stopping the production of proteins. [3] Chloramphenicol was discovered after being isolated from Streptomyces venezuelae in 1947. [6] Its chemical structure was identified and it was first synthesized in 1949. See more Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes use as an eye ointment to treat conjunctivitis. By mouth or by injection into a vein, it is used to treat meningitis See more Aplastic anemia The most serious side effect of chloramphenicol treatment is aplastic anaemia. This effect is rare but sometimes fatal. The risk of AA … See more Chloramphenicol is a bacteriostatic agent, inhibiting protein synthesis. It prevents protein chain elongation by inhibiting the peptidyl transferase activity of the bacterial ribosome. … See more Names Chloramphenicol is available as a generic worldwide under many brandnames and also under various generic names in eastern Europe and Russia, including chlornitromycin, levomycetin, and chloromycetin; the … See more The original indication of chloramphenicol was in the treatment of typhoid, but the presence of multiple drug-resistant Salmonella Typhi has meant it is seldom used for this indication except when the organism is known to be sensitive. In low-income … See more Chloramphenicol is extremely lipid-soluble; it remains relatively unbound to protein and is a small molecule. It has a large apparent volume of distribution and penetrates … See more Chloramphenicol was first isolated from Streptomyces venezuelae in 1947 and in 1949 a team of scientists at Parke-Davis including Mildred Rebstock published their identification of the … See more WebJun 14, 2024 · Tetracyclines are one of the most used class of antibiotics . in both human and animal medicine because of . availability, ... Chloramphenicol is a semisynthetic, broad-spectrum .
Chloramphenicol Drugs BNF NICE
WebS01AA01 - chloramphenicol ; Belongs to the class of antibiotics. Used in the treatment of eye infections. S02AA01 - chloramphenicol ; Belongs to the class of antiinfectives used in the treatment of ear infections. J01BA01 - chloramphenicol ; Belongs to the class of amphenicols. Used in the systemic treatment of infections. WebChloramphenicol is a broad-spectrum antimicrobial agent. It acts by inhibiting protein synthesis. Its high lipid solubility results in rapid absorption, a large volume of distribution, and accelerated penetration into almost all tissues. Aplastic anemia and bone marrow suppression are chloramphenicol's most serious adverse effects in humans. clifton tx city park
Dual targeting of the class V lanthipeptide antibiotic cacaoidin
WebApr 12, 2024 · Antibiotic-resistant bacteria in aquatic environments. Antibiotic resistance in clinical settings is widely known; however, this problem does not restrict to hospitals (Berglund 2015).The record of the prevalence of antibiotic resistance genes (ARGs) in aquatic environments from different sources has been increasingly common, which … WebDRUG CLASS AND MECHANISM: Chloramphenicol is a man-made antibiotic. It slows growth of bacteria by preventing them from producing important proteins that they need … WebMajor Classes of Antibiotics Name Examples Spectrum Mode of Action Biological Source Beta-Lactams Penicillins Penicillin, amoxicillin/clavulanate (Clavamox, … clifton tx elementary school