WebCyp17a1: Gene Name: Cytochrome P450, family 17, subfamily a, polypeptide 1: Aliases: Cyp17, p450c17: RefSeq: NC_000085.6 NT_039687.8: Ensembl: … CYP17A1 is a member of the cytochrome P450 superfamily of enzymes localized in the endoplasmic reticulum. Proteins in this family are monooxygenases that catalyze synthesis of cholesterol, steroids and other lipids and are involved in drug metabolism. CYP17A1 has both 17α-hydroxylase activity (EC … See more Cytochrome P450 17A1 (steroid 17α-monooxygenase, 17α-hydroxylase, 17-alpha-hydroxylase, 17,20-lyase, 17,20-desmolase) is an enzyme of the hydroxylase type that in humans is encoded by the … See more Gene The CYP17A1 gene resides on chromosome 10 at the band 10q24.3 and contains 8 exons. The cDNA of this gene spans a length of … See more Mutations in this gene are associated with rare forms of congenital adrenal hyperplasia, specifically 17α-hydroxylase deficiency/17,20-lyase deficiency See more • Pregnenolone • 17α-Hydroxypregnenolone • Progesterone • 17α-Hydroxyprogesterone See more Expression of CYP17A1 has been found in all of the traditional steroidogenic tissues except the placenta, including the zona reticularis See more CYP17A1 inhibitors Currently, the FDA has approved only one CYP17A1 inhibitor, abiraterone, which contains a steroidal scaffold that is similar to the endogenous … See more • Biology portal • Steroidogenic enzyme • Cytochrome P450 oxidoreductase deficiency See more
Unveiling the crucial intermediates in androgen production PNAS
WebCYP11A1 (D8F4F) Rabbit mAb. #14217. 使用 CYP11A1 (D8F4F) Rabbit mAb(绿色)对 NCI-H295R(左,阳性)和 SW-13(右,阴性)细胞进行共聚焦免疫荧光分析。. 肌动蛋 … WebCYP11A1蛋白;细胞色素P450家族成员11A1 (CYP11A1)重组蛋白两个建议:. 1、用非变性纯化样品去做EK酶切、纯化。. 如果融合蛋白的降解是从N端开始的,而C端没有降解, … importance of global education
A single-amino-acid in-frame deletion in CYP17A1 results in …
Web1 day ago · 【共同社4月13日电】在全球大受欢迎的日本作家村上春树(74岁)的小说新作《城市及其不确定的墙》13日发售。这是继《刺杀骑士团长》(全2册)之后时隔约6年 … WebMay 5, 2011 · 2013-11-15 白血病发生与什么基因有关 2024-02-15 基因检测出风险,还能投保么 2015-07-24 肝细胞基因点位检测是什么 2014-04-27 什么是荷尔蒙? 2014-05-01 … WebCytochrome P450 17A1 (CYP17A1; also P450c17and P450sccII) is a critically important enzyme in humans that catalyzes the formation of all endogenous androgens. It is an atypical cytochrome P450 enzyme in that it catalyzes two distinct types of substrate oxidation. Through its hydroxylase activity, it catalyzes the 17α-hydroxylation of … importance of giving students choices