http://amigo.geneontology.org/amigo/term/GO:0016600 WebOct 26, 2024 · Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe …
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WebDec 1, 2011 · Flotillins have been implicated in myriad processes that include endocytosis, signal transduction and regulation of the cortical cytoskeleton, yet the molecular … WebMar 21, 2024 · ATP-binding cassette, sub-family A (ABC1), member 1 forms a complex with syntaxin 13 and flotillin-1, residing at the plasma membrane and in phagosomes; Flotillin-1, a marker of rafts, accumulates in lysosomes of neurons in Alzheimer's disease; Recombinant flotillin-1 was purified and characterized in in large quantity and high purity. grandville towers
Flotillin-1-enriched Lipid Raft Domains Accumulate on Maturing ...
WebMar 2, 2012 · We here show that flotillin-1 forms a complex with CRAF, MEK1, ERK, and KSR1 (kinase suppressor of RAS) and that flotillin-1 knockdown leads to a direct … WebJan 1, 2024 · Flotillin-2 was originally cloned in 1994 by Schroeder et al. by immunoscreening of a human keratinocyte cDNA library using the monoclonal antibody ECS-1 against cultured keratinocytes. ... palmitoylation, and hydrophobic interaction. Flotillin-2 is mainly found in a hetero-oligomeric complex with its homologue flotillin-1, … WebJul 3, 2024 · Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are associated with obesity. They are accompanied by increased levels of free cholesterol in the liver. Most free cholesterol resides within the plasma membrane. We assessed the impact of adding or removing free cholesterol on the function and … grandville schools closed