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Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic ...

WebOverall design: p62F/F and Tsc1 F/F mice (Mori et al., 2009; Muller et al., 2013) were backcrossed to C57BL/6 mice for at least 7 generations, and then bred with Alb-Cre transgenic mice (also on C57BL/6 background) to generate p62F/F; Alb-Cre (p62Δhep) and Tsc1F/F; Alb-Cre (Tsc1Δhep)mice, respectively. p62Δhep mice were crossed to Tsc1Δhep ... Web该TSC1 Polyclonal Antibody. This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. philips 55pus7506/12 review

利用肝脏特异性TSC1敲除小鼠建立酒精性肝炎模型 免疫 肝细胞 纤 …

WebWe allowed Tsc1f/f; Rosa26-CreERT2 glioma cells to form spheres in culture and then added 4-hydroxytamoxifen (4-OHT) to delete the Tsc1 gene. First, we confirmed that 4-OHT efficiently induced Tsc1 deletion in these sphere cells, as evidenced by the disappearance of TSC1 protein from lysates of sphere cells that had been cultured with 4-OHT ( Fig. 2 A ). WebMar 1, 2024 · All mice were finally euthanized with medical carbon dioxide and cervical dislocation at the end point time. Tsc1f/f have published the research work: Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasing osteopontin and Stat3 signaling, in the Journal: (JOURNAL) of 21/Dec/2024 WebCatalogue Number 160865: Antigen/Gene or Protein Targets Tsc1/Hamartin trust information form